The goal of this project is to find and verify new overlapping protein-coding DNA-sequences in prokaryotes and to understand the underlying mechanisms with the help of models from information and communication theory. This is a collaboration project with researchers from the Institute of Telecommunications and Applied Information Theory – TAIT at Ulm University and the Department of Microbiology at the Central Institute for Food and Nutrition Research (ZIEL) at Technische Universität München, which is funded by the German Research Foundation (DFG) priority programme “Information and Communication Theory in Molecular Biology” (InKoMBio) SPP 1395. Read more.
Analyzing Structure-Activity Relationships of Large Screening Experiments
The goal of this project is to develop advanced visual analytics tools to help biochemists engineer molecules with desired properties through the visual and interactive analysis of data generated by high-throughput screening experiments. The project is part of the INCIDE initiative at the University of Konstanz a joint collaboration between the Graduate School Chemical Biology (Excellence Initiative, KORS-CB) and the Department of Computer Science and Information Science.
Completed Research Projects
Using alignments of functionally equivalent proteins, we addressed the question what restrictions are protein sequences subjected to. Read more.